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1.
Article in English | IMSEAR | ID: sea-124329

ABSTRACT

AIM: The mechanisms responsible for bowel disturbances in celiac disease are still unknown. Small bowel motor abnormalities may be involved in this pathological condition; however, there is no study addressing small bowel transit in patients of celiac disease from Northern India. METHOD: The mouth-to-cecum transit time was studied in 80 celiac patients and 80 age and sex matched apparently healthy controls. RESULTS: Orocecal transit time in celiac patients was significantly delayed being 180+/-10.6 minutes (Mean+/-SE) as compared to 105+/-12.4 minutes in apparently healthy controls. CONCLUSION: This prolonged orocecal transit time could be due to impaired small bowel function (deranged motility) in patients with celiac disease.


Subject(s)
Adult , Aged , Case-Control Studies , Cecal Diseases/physiopathology , Cecum/physiopathology , Cohort Studies , Female , Gastrointestinal Transit/physiology , Humans , Male , Middle Aged , Myoelectric Complex, Migrating/physiology , Young Adult
2.
Article in English | LILACS | ID: lil-342123

ABSTRACT

PURPOSE: to describe the patterns of the gastric myoelectrical activity, pre-and postprandially, in clinically stable neonates of different gestational ages, during their first two weeks of life by means of Electrogastrography. PATIENTS AND METHODS: Electrogastrography was recorded in forty-five clinically stable neonates of different gestational ages (group I: 15 neonates of > 37 weeks, group II: 15 premature neonates of 32-37 weeks; Group III: 15 premature neonates of 28-31 weeks) receiving intermittent enteral feedings during their first two weeks of life. Electrogastrography recordings were performed for 1 hour pre-and postprandially. The Electrogastrography signal was recorded using the portable MicroDigitrapper Electrogastrography recording device and after motion artifacts were deleted, the remaining Electrogastrography data were submitted to quantitative analysis based on the "Running Spectrum Analysis". RESULTS: The percentages of normogastria, pre-and postprandially were greater than the percentages of gastric dysrythmias in all three studied groups. Furthermore, all neonates had the mean values of the Electrogastrography dominant frequency predominantly within the normogastria range, in both periods analyzed. There were no significant differences in the relative change of the Electrogastrography dominant power among the groups. CONCLUSION: This study demonstrates that the Electrogastrography patterns are similar between premature and full term neonates during the pre-and postprandial periods. The results of this study also indicate that the gastric myoelectrical activity in premature and full term neonates is immature, as compared to that described for older neonates, children and adults


Subject(s)
Humans , Male , Female , Electromyography/methods , Gastrointestinal Motility/physiology , Infant, Newborn/physiology , Infant, Premature/physiology , Stomach/physiology , Gestational Age , Myoelectric Complex, Migrating/physiology , Postprandial Period
3.
Recife; s.n; 1995. 100 p. tab, graf. (BR).
Thesis in Portuguese | LILACS | ID: lil-206643

ABSTRACT

O granuloma esquistossomótico determina lesSes anatomopatológicas a nível dos plexos mioentéricos e submucoso do trato gastrointestinal, secundárias a reaçSes imunológicas. Essas lesSes podem produzir alteraçSes da motilidade intestinal. O objetivo deste estudo foi determinar o padrÝo da atividade mioelétrica do cólon esquerdo em pacientes esquistossomóticos, na forma hepato-esplênica. Foram utilizados dezessete pacientes, sendo doze esquistossomóticos e cinco do grupo controle, submetidos a histerectomia. Eletrodos bipolares cobertos por Téflon (fio de marcapasso) foram implantados a nível da tênia anterior do cólon esquerdo, em número de três pares, distando cinco centímetros (cm) um do outro, estando o último eletrodo a vinte cm da reflexÝo peritoneal. Após a recuperaçÝo do íleo paralítico pós-operatório, iniciou-se o processo da coleta de dados . Foi utilizado um sistema de aquisiçÝo de dados (DATA Q Série 200), que capta frequencia entre 0,02 a 10 Hz. Antes de serem registrados na placa de aquisiçÝo de dados, os sinais foram amplificados com um ganho de 1000 vezes, e armazenados em disquetes, utilizando-se um software de aquisiçÝo (WINDAQ 200), que roda no ambiente WINDOWS. As frequências situadas abaixo de 0,3 Hz sÝo selecionadas para a Atividade Elétrica de Controle (AEC) e as frequências entre 0,7 e 10Hz selecionadas para a Atividade Elétrica de resposta (AER). Os resultados obtidos evidenciaram uma AEC com predomínio da baixa frequencia nos dois grupos de pacientes esquistossomóticos apresentou uma AEC estatisticamente menor, quando comparado com o grupo controle (p=0,009). A AER de curta duraçÝo também apresentou uma diferença estatísticamente significativa (p=0,037). Ou seja, o grupo de pacientes esquistossomóticos apresentaram uma média de 96,56 contraçSes por hora, enquanto que os pacientes do grupo controle apresentaram em média 128,83 contraçSes por hora. NÝo houve diferenças relacionadas à duraçÝo da AER de curta duraçÝo. A AER de longa duraçÝo nÝo apresentou diferença estatisticamente significativa, tanto em relaçÝo ao número, quanto à duraçÝo, assim como nÝo houve diferenças relacionadas ao "cluster". O autor conclui que os pacientes portadores de esquistossomose hepatoesplênica apresentam uma AEC e uma AER de curta duraçÝo menores do que o grupo controle, nÝo havendo diferenças no que tange à AER de longa duraçÝo e o número e duraçÝo dos "cluster"


Subject(s)
Humans , Male , Female , Adult , Colon , Myoelectric Complex, Migrating/physiology , Schistosomiasis mansoni/surgery , Electromyography , Gastrointestinal Motility , Hysterectomy
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